Therapeutic Antibodies – Jacob M. Waugh, Michael D. Dake, Illustris Pharmaceuticals Inc
Abstract for “Methods of topical delivery: Compositions”
This article describes compositions that can be used to topically deliver an active agent. A composition may contain one or more active ingredients and approximately 0.001 wt. From 1% to 10 wt. % of an extracellular matrix component with an average molecular mass of approximately 2,000 to 20,000 daltons. Extracellular components include collagen, fibronectin and hyaluronic acids, as well as fragments and combinations thereof.
Background for “Methods of topical delivery: Compositions”
“Decoy Molecules”
“Hyaluronidase/Elastase”
“Active Agents”
“Antigens/Antibody Fragments”
“Tracer/Contrast Agent”
“Neurotoxins”
“Sensation Modifying agents”
“Therapeutic Cells”
“Compositions”
“Permeation Enhancers”
“Transdermal Patches”
“Methods for Using Compositions”
“Skin Disorders”
“Hair Disorders”
“Other Disorders”
“Cancer Therapy”
“Non-Invasive Topical Diagnostics.”
“Administration”
“Aerosol Delivery”
“EXAMPLES”
“Example 1”
“Hyaluronic acid and Biomimetic peptidides”
“Example 2”
“Hylauronic acid and Salicylate”
“Example 3”
“Hylauronic acid and a Steroid”
“Example 4”
“Elastin, Lidocaine”
“Example 5”
“Hylauronic acid and Minocycline”
“Example 6”
“Example 7”
“Hyaluronic acid and Gabapentin”
“Example 8”
“Hyaluronic Acid and Palmitoyl-Lysine-Threonine-Threonine-Lysine-Serine”
“Example 9”
“Example 10”
“Example 11”
“Example 12”
“Example 13”
“Functional antioxidant capacity”
“Example 14”
“FTIC-Dextran Confocal skin analysis”
“Example 15”
“Example 16”
“Collagen and Vitamin C.”
“Collagen and Diclofenac.”
“Elastin and Niacinamide.”
“Elastin and Naproxen.”
“Topical Administration of Bimatoprost to Hair Growth”
“Decoy-Enhanced Hair Color Treatment for Shafts”
“Bimatoprost for Dry Eyes”
“Example 17”
“Topical Peptidyl Decoy Mediated Enhancement in Salicylate Delivery through Mucosal Surfaces”
“Example 18”
“Topical Use of Sildenafil”
“Example 19”
“Example 20”
“Topical Enhancement Of Bone and Periosteal Permeation Via Saccharidyl/Peptidyl Decoys”
“Example 21”
“Larger Molecular Weight Decoys Flux”
“Example 22”
“Larger Ha Abolishes Flux?” Addition of HighMW?Impurity To Pure Low MW Composition
“Example 23”
“Example 24”
“Proof of Concept 150,000 da Facial Application”
“Example 25”
“Topical Axillary Use of Botulinum Toxin A.”
“Example 26”
“Example 27”
“Example 28”
“Example 29”
“Example 30”
“Diagnostic penetration of antibodies across intact skin”
“Example 31”
“Diagnostic penetration of antibodies across tissue barriers post excisional biopsy”
“Example 32”
“Interstitial Diagnostic patch”
“Example 33”
“Emergency Diagnostics”
“Example 34”
“Hyaluronidase” and Lidocaine
“Example 35”
“Elastase & Minocycline”
“Example 36”
“Elastase, Vitamin C”
“Example 37”
“Topical Administration of Bimatoprost to Hair Growth”
“Example 38”
“Bimatoprost for Dry Eyes”
Summary for “Methods of topical delivery: Compositions”
“Decoy Molecules”
“Hyaluronidase/Elastase”
“Active Agents”
“Antigens/Antibody Fragments”
“Tracer/Contrast Agent”
“Neurotoxins”
“Sensation Modifying agents”
“Therapeutic Cells”
“Compositions”
“Permeation Enhancers”
“Transdermal Patches”
“Methods for Using Compositions”
“Skin Disorders”
“Hair Disorders”
“Other Disorders”
“Cancer Therapy”
“Non-Invasive Topical Diagnostics.”
“Administration”
“Aerosol Delivery”
“EXAMPLES”
“Example 1”
“Hyaluronic acid and Biomimetic peptidides”
“Example 2”
“Hylauronic acid and Salicylate”
“Example 3”
“Hylauronic acid and a Steroid”
“Example 4”
“Elastin, Lidocaine”
“Example 5”
“Hylauronic acid and Minocycline”
“Example 6”
“Example 7”
“Hyaluronic acid and Gabapentin”
“Example 8”
“Hyaluronic Acid and Palmitoyl-Lysine-Threonine-Threonine-Lysine-Serine”
“Example 9”
“Example 10”
“Example 11”
“Example 12”
“Example 13”
“Functional antioxidant capacity”
“Example 14”
“FTIC-Dextran Confocal skin analysis”
“Example 15”
“Example 16”
“Collagen and Vitamin C.”
“Collagen and Diclofenac.”
“Elastin and Niacinamide.”
“Elastin and Naproxen.”
“Topical Administration of Bimatoprost to Hair Growth”
“Decoy-Enhanced Hair Color Treatment for Shafts”
“Bimatoprost for Dry Eyes”
“Example 17”
“Topical Peptidyl Decoy Mediated Enhancement in Salicylate Delivery through Mucosal Surfaces”
“Example 18”
“Topical Use of Sildenafil”
“Example 19”
“Example 20”
“Topical Enhancement Of Bone and Periosteal Permeation Via Saccharidyl/Peptidyl Decoys”
“Example 21”
“Larger Molecular Weight Decoys Flux”
“Example 22”
“Larger Ha Abolishes Flux?” Addition of HighMW?Impurity To Pure Low MW Composition
“Example 23”
“Example 24”
“Proof of Concept 150,000 da Facial Application”
“Example 25”
“Topical Axillary Use of Botulinum Toxin A.”
“Example 26”
“Example 27”
“Example 28”
“Example 29”
“Example 30”
“Diagnostic penetration of antibodies across intact skin”
“Example 31”
“Diagnostic penetration of antibodies across tissue barriers post excisional biopsy”
“Example 32”
“Interstitial Diagnostic patch”
“Example 33”
“Emergency Diagnostics”
“Example 34”
“Hyaluronidase” and Lidocaine
“Example 35”
“Elastase & Minocycline”
“Example 36”
“Elastase, Vitamin C”
“Example 37”
“Topical Administration of Bimatoprost to Hair Growth”
“Example 38”
“Bimatoprost for Dry Eyes”
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